Metamizole
Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1].
Product Specifications
CAS Number
50567-35-6
Product Name Alternative
Dipyrone (free base) ; Methamizole
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/metamizol.html
Solubility
10 mM in DMSO
Smiles
O=C1C(N(CS(=O)(O)=O)C)=C(C)N(C)N1C2=CC=CC=C2
Molecular Formula
C13H17N3O4S
Molecular Weight
311.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Heidari R, et, al. Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole-Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine. Adv Pharm Bull. 2014;4 (1) :21-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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