Metamizole

Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1].

Product Specifications

CAS Number

[50567-35-6]

Product Name Alternative

Dipyrone (free base) ; Methamizole

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/metamizol.html

Solubility

10 mM in DMSO

Smiles

O=C1C(N(CS(=O)(O)=O)C)=C(C)N(C)N1C2=CC=CC=C2

Molecular Formula

C13H17N3O4S

Molecular Weight

311.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Heidari R, et, al. Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole-Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine. Adv Pharm Bull. 2014;4 (1) :21-8.