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Glycerophospholipids, cephalins

Glycerophospholipids and cephalins are a class of phospholipid compounds and important components of neural membranes. Glycerophospholipids and cephalins are hydrolysis substrates of phospholipase (such as PLA2, PLC, and PLD) . After complete hydrolysis, they produce 1 mol of glycerol, phosphate, ethanolamine, and 2 mol of fatty acids, respectively. Glycerophospholipids and cephalins can maintain membrane structure, fluidity, and ion permeability, and serve as precursors of second messengers such as arachidonic acid and diacylglycerol. Glycerophospholipids and cephalins can regulate signal transduction, cell apoptosis, and membrane transport, and are used in the study of neurodegenerative diseases (such as Alzheimer's disease) [1][2].

Product Specifications

CAS Number

[39382-08-6]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H331, H336, H351, H361, H372, H402

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/glycerophospholipids-cephalins.html

Purity

88.59

Solubility

THF : 100 mg/mL

Smiles

[Glycerophospholipids,cephalins]

Precautions

H302, H315, H319, H331, H336, H351, H361, H372, H402

References & Citations

[1]Frisardi V, et al. Glycerophospholipids and glycerophospholipid-derived lipid mediators: a complex meshwork in Alzheimer's disease pathology. Prog Lipid Res. 2011 Oct;50 (4) :313-30.|[2]Farooqui AA, et al. Glycerophospholipids in brain: their metabolism, incorporation into membranes, functions, and involvement in neurological disorders. Chem Phys Lipids. 2000 Jun;106 (1) :1-29.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Curated Selection

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