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FAK-IN-8

FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 μM) . FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1].

Product Specifications

CAS Number

1374959-91-7

UNSPSC

12352005

Target

FAK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fak-in-8.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NN=C(C2=CC=C(Cl)C=C2)S1)C3=CC(Cl)=CC=C3O

Molecular Formula

C15H9Cl2N3O2S

Molecular Weight

366.22

References & Citations

[1]Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20 (9) :2789-95.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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