FAK-IN-8
FAK-IN-8 (compound 5h) is a FAK inhibitor (IC50=5.32 μM) . FAK-IN-8 has good anti-proliferative activity and can be used in cancer research[1].
Product Specifications
CAS Number
1374959-91-7
UNSPSC
12352005
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fak-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NN=C(C2=CC=C(Cl)C=C2)S1)C3=CC(Cl)=CC=C3O
Molecular Formula
C15H9Cl2N3O2S
Molecular Weight
366.22
References & Citations
[1]Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20 (9) :2789-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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