EGFR-IN-64
Product Specifications
UNSPSC Description
EGFR-IN-64 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 0.33 μM. EGFR-IN-64 shows anticancer activity[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-64.html
Solubility
10 mM in DMSO
Smiles
O=C(N1N=C(/C=C/C2=CC=C(OC)C=C2)CC1C3=CC=C(OC)C=C3)N
Molecular Weight
351.40
References & Citations
[1]George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147995/EGFR-IN-64-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147995/
Clinical Information
No Development Reported
CAS Number
2416924-93-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6298664-01 0.1 mL
FCGR3A, CT (FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, FcR-10, IgG Fc receptor III-2, CD16a) (MaxLight 405)
Ask
View Details 
MBS6298664-02 5x 0.1 mL
FCGR3A, CT (FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, FcR-10, IgG Fc receptor III-2, CD16a) (MaxLight 405)
Ask
View Details