DNA Gyrase-IN-5
DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains[1].
Product Specifications
CAS Number
2417016-23-8
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dna-gyrase-in-5.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(/N=C/C2=C(C3=CC=C(Br)C=C3)NC4=C2C=CC=C4)N(C5=CC=C(Cl)C=C5)N=C1
Molecular Formula
C25H15BrClN5
Molecular Weight
500.78
References & Citations
[1]Liu H, et al. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase. Bioorg Chem. 2020 Jun;99:103807.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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