hCA I-IN-2
Product Specifications
UNSPSC Description
hCA I-IN-2 (Compound 6d) is a selective human carbonic anhydrase I (hCA I) inhibitor with Ki values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hca-i-in-2.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)N2C=C(N=N2)CN3C=C(C4=CC=CC=C43)/C=C/C(C5=CC=C(C=C5)Br)=O)=O
Molecular Weight
562.44
References & Citations
[1]Singh P, et al. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg Chem. 2020 Jun;99:103839.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147986/hCA-I-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147986/
Clinical Information
No Development Reported
CAS Number
2417232-12-1
Curated Selection
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