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HCAXII-IN-3

HCAXII-IN-3 (Compound 6o) is a selective human carbonic anhydrase XII (hCAXII) inhibitor with a Ki of 10.0 nM[1].

Product Specifications

CAS Number

2417232-24-5

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hcaxii-in-3.html

Solubility

10 mM in DMSO

Smiles

NS(=O)(C1=CC=C(C=C1)N2C=C(N=N2)CN3C=C(C4=CC=CC=C43)/C=C/C(C5=C(C=CC=C5)Br)=O)=O

Molecular Formula

C26H20BrN5O3S

Molecular Weight

562.44

References & Citations

[1]Singh P, et al. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg Chem. 2020 Jun;99:103839.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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