GABA-AT-IN-1
GABA-AT-IN-1 (Compound 6) is a γ-aminobutyric acid aminotransferase (GABA-AT) inhibitor and significantly elevates the mouse brain GABA level. GABA-AT-IN-1 has the ability to cross the BBB and can be used as an anticonvulsant[1].
Product Specifications
CAS Number
242148-96-5
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gaba-at-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NN(C(C1=C2C=CC=C1)=O)C2=O)COC3=CC=C(C(O4)=C3CC=C)C(C)=CC4=O
Molecular Formula
C23H18N2O6
Molecular Weight
418.40
References & Citations
[1]Abd-Allah WH, et al. Design, synthesis and docking studies of novel benzopyrone derivatives as anticonvulsants. Bioorg Chem. 2020 May;98:103738.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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