Antifungal agent 34
Antifungal agent 34 (compound 6i) is a potent antifungal agent. Antifungal agent 34 shows a potent antifungal activity against Candida albicans, with a MIC of 4 µg/mL. Antifungal agent 34 shows significant inhibition on Candida albicans hyphae and biofilm development. Antifungal agent 34 exhibits no cytotoxicity to mammalian cells[1].
Product Specifications
CAS Number
2036123-97-2
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-34.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@]2(C3=CC(OC(F)(F)F)=CC=C3N1)[C@@]4(C(/C(CN(C4)/C=C/C5=CC=CC=C5)=C/C6=CC=C(C=C6)C)=O)[C@@H](C7=CC=C(C=C7)C)[C@@H](N2)CC8=CC=CC=C8
Molecular Formula
C46H40F3N3O3
Molecular Weight
739.82
References & Citations
[1]Lawson S, et al. Dispiropyrrolidine tethered piperidone heterocyclic hybrids with broad-spectrum antifungal activity against Candida albicans and Cryptococcus neoformans. Bioorg Chem. 2020 Jul;100:103865.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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