EGFR-IN-63
Product Specifications
UNSPSC Description
EGFR-IN-63 is an EGFR inhibition (IC50: 0.096 μM) and it has anticancer activity in MCF-7 cells (IC50: 2.49 μM).
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-63.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC2=C(NC3=NC4=CC=CC=C4S3)N=C(C5=CC=CN=C5)N=C2C=C1
Molecular Weight
434.31
References & Citations
[1]Heba Abdelrasheed Allam, et al, Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents, Bioorg Chem. 2020 May;98:103726
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147967/EGFR-IN-63-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147967/
Clinical Information
No Development Reported
CAS Number
2414635-72-4
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