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EGFR-IN-63

EGFR-IN-63 is an EGFR inhibition (IC50: 0.096 μM) and it has anticancer activity in MCF-7 cells (IC50: 2.49 μM) .

Product Specifications

CAS Number

2414635-72-4

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-63.html

Solubility

10 mM in DMSO

Smiles

BrC1=CC2=C(NC3=NC4=CC=CC=C4S3)N=C(C5=CC=CN=C5)N=C2C=C1

Molecular Formula

C20H12BrN5S

Molecular Weight

434.31

References & Citations

[1]Heba Abdelrasheed Allam, et al, Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents, Bioorg Chem. 2020 May;98:103726

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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