COX-2-IN-24
COX-2-IN-24 is an orally active inhibitor of COX-2 with IC50 value of 0.17 μM, shows anti-inflammatory and low ulcerogenic activities.
Product Specifications
CAS Number
2417995-10-7
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cox-2-in-24.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC(C(N2C3=CC=C(Br)C=C3)=NNC2=S)=CC(NCCCC)=C1OC4=CC=CC=C4)(N)=O
Molecular Formula
C24H24BrN5O3S2
Molecular Weight
574.51
References & Citations
[1]Tarek S Ibrahim, et al. Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold. Bioorg Chem. 2020 Jul;100:103878.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
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