Glycosyltransferase-IN-1
Glycosyltransferase-IN-1 (compound 5m) is a potent glycosyltransferase inhibitor, with an IC50 of 82.8 μM. Glycosyltransferase-IN-1 shows antibacterial activity, with MIC values of 6 μg/mL for MSSA, MRSA, B. subtilis and 12 μg/mL for E. coli[1].
Product Specifications
UNSPSC
12352005
Target
Glycosyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/glycosyltransferase-in-1.html
Solubility
10 mM in DMSO
Smiles
CCCCC1=CC=C(C=C1)N2C(/C(C3=C2C=CC=C3)=N/NC(N)=N)=O
Molecular Formula
C19H21N5O
Molecular Weight
335.40
References & Citations
[1]Wang Y, et al. Hydrophobic substituents on isatin derivatives enhance their inhibition against bacterial peptidoglycan glycosyltransferase activity. Bioorg Chem. 2020 Apr;97:103710.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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