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HCA VB-IN-1

HCA VB-IN-1 (compound 15) is a potent and selective hCA VB (carbonic anhydrase) inhibitor, with a KI of 515.7 nM[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hca-vb-in-1.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C(C)=C1)NC(NOS(N)(=O)=O)=O

Molecular Formula

C9H13N3O4S

Molecular Weight

259.28

References & Citations

[1]Poli G, et al. N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions. Bioorg Chem. 2020 Jul;100:103896.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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