TbPTR1 inhibitor 1
TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM) [1].
Product Specifications
CAS Number
2499713-65-2
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tbptr1-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(N(CC)CC2=CN=C(N=C(N)N=C3N)C3=N2)C=C1)C4=CC=CC=C4
Molecular Formula
C22H21N7O
Molecular Weight
399.45
References & Citations
[1]Pöhner I, et al. Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J Med Chem. 2022 Jun 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Trypanosoma
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2609333-01 48 Well
Bovine Interleukin 1 Receptor Antagonist (IL-1RA) ELISA kit
Sign In for Pricing
View Details MBS2609333-02 96 Well
Bovine Interleukin 1 Receptor Antagonist (IL-1RA) ELISA kit
Sign In for Pricing
View Details