AKT-IN-13

Product Specifications

CAS Number

[2459489-51-9]

UNSPSC Description

AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1].

Target Antigen

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/akt-in-13.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(CC1)C2=C3C(NC(C[C@H]3C)=O)=NC=N2)[C@@H](C4=CC=C(C=C4)Cl)CNC(C)C

Molecular Weight

470.99

References & Citations

[1]Ma C, et al. Discovery of Clinical Candidate NTQ1062 as a Potent and Bioavailable Akt Inhibitor for the Treatment of Human Tumors. J Med Chem. 2022 Jun 23;65(12):8144-8168.