AKT-IN-13
Product Specifications
UNSPSC Description
AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1].
Target Antigen
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akt-in-13.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(CC1)C2=C3C(NC(C[C@H]3C)=O)=NC=N2)[C@@H](C4=CC=C(C=C4)Cl)CNC(C)C
Molecular Weight
470.99
References & Citations
[1]Ma C, et al. Discovery of Clinical Candidate NTQ1062 as a Potent and Bioavailable Akt Inhibitor for the Treatment of Human Tumors. J Med Chem. 2022 Jun 23;65(12):8144-8168.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147937/AKT-IN-13-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147937/
Clinical Information
No Development Reported
CAS Number
2459489-51-9
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