ACC1/2-IN-1
ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research[1].
Product Specifications
CAS Number
2350219-22-4
UNSPSC
12352005
Target
Acetyl-CoA Carboxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/acc1-2-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O2)C=C3C(CCC(C)(C)O3)=C1)CC42CCN(C(C5=CC=C6NC(C7=CC8=C(NC=C8)C=C7)=NC6=C5)=O)CC4
Molecular Formula
C34H32N4O4
Molecular Weight
560.64
References & Citations
[1]Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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