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Apoptotic agent-3

Apoptotic agent-3 (compound 15f) promotes apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway and activation of the Caspase 3 pathway. Apoptotic agent-3 exhibits anti-proliferative activities and can be used for cancer research[1].

Product Specifications

CAS Number

2482310-23-4

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family; Caspase

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/apoptotic-agent-3.html

Purity

98.19

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C2=CS/C(N2C3=CC=CC=C3)=N/N=C4C5=C(C6=NC7=CC=CC=C7N=C6\4)C=CC=C5)C=C1

Molecular Formula

C31H21N5OS

Molecular Weight

511.60

References & Citations

[1]Fayed EA, et al. In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 Jul;100:103951.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Bax; Bcl-2; Caspase 3

Available Sizes

Frequently Asked Questions

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