Apoptotic agent-3
Apoptotic agent-3 (compound 15f) promotes apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway and activation of the Caspase 3 pathway. Apoptotic agent-3 exhibits anti-proliferative activities and can be used for cancer research[1].
Product Specifications
CAS Number
[2482310-23-4]
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptotic-agent-3.html
Purity
98.19
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C2=CS/C(N2C3=CC=CC=C3)=N/N=C4C5=C(C6=NC7=CC=CC=C7N=C6\4)C=CC=C5)C=C1
Molecular Formula
C31H21N5OS
Molecular Weight
511.60
References & Citations
[1]Fayed EA, et al. In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 Jul;100:103951.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax; Bcl-2; Caspase 3
Available Sizes
Curated Selection
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