PI3K/Akt/mTOR-IN-3
PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the concentration of 4 μM. PI3K/Akt/mTOR-IN-3 induces cell apoptosis and S phase arrest[1].
Product Specifications
CAS Number
2457245-94-0
UNSPSC
12352211
Target
Akt; Apoptosis; mTOR; PI3K
Type
Reference compound
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-akt-mtor-in-3.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(C(C[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(NCC=C)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=C)=O
Molecular Formula
C34H51NO2
Molecular Weight
505.77
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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