CDK9-IN-18
Product Specifications
UNSPSC Description
CDK9-IN-18 is a potent CDK9 inhibitor. CDK9-IN-18 blocks the phosphorylation function of kinase CDK9. CDK9-IN-18 exhibits both good anticancer activity and low cellular activity. CDK9-IN-18 induces apoptosis.
Target Antigen
Apoptosis; CDK
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N1)=CC2=C1C=CC(NC3=NC=CC(C4=CC=CN=C4)=N3)=C2)N/N=C/C5=CNC6=C5C=CC=C6
Molecular Weight
472.50
References & Citations
[1]Hu H, et al. Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors. Bioorg Chem. 2020 Sep;102:104064.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147905/CDK9-IN-18-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147905/
Clinical Information
No Development Reported
CAS Number
1804127-83-0
Curated Selection
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