HIV-IN-5
Product Specifications
UNSPSC Description
HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) [1].
Target Antigen
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(OCO2)C2=C1)OC3=CC=C(C(CSC4=NC(CC5=CC=C(OCO6)C6=C5)=C(CC)C(N4)=O)=O)C=C3
Molecular Weight
572.59
References & Citations
[1]Yi-MingLi, et al. Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. September 2020;102:104041.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147904/HIV-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147904/
Clinical Information
No Development Reported
CAS Number
2459929-62-3
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