VEGFR-2-IN-24
VEGFR-2-IN-24 is a potent VEGFR-2 inhibitor with IC50 value of 0.22 μM. VEGFR-2-IN-24 can be used for tumor research[1].
Product Specifications
CAS Number
[2455414-26-1]
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-24.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC)C1=CC=C(NC(C2=CC=C(NC(CN(C/3=O)C(SC3=C/C4=CC=CC=C4)=O)=O)C=C2)=O)C=C1
Molecular Formula
C28H23N3O6S
Molecular Weight
529.56
References & Citations
[1]El-Adl K, et al. Design, synthesis, molecular docking and anticancer evaluations of 5-benzylidenethiazolidine-2,4-dione derivatives targeting VEGFR-2 enzyme. Bioorg Chem. 2020 Sep;102:104059.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
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