Apoptosis inducer 9
Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents[1].
Product Specifications
CAS Number
2551067-10-6
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-9.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@]4(OC(C)(CCC4)C)C)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)OC(CSC6=NN=CN6)=O)C)([H])CC1)C
Molecular Formula
C34H55N3O4S
Molecular Weight
601.88
References & Citations
[1]Xiao S, et al. Novel panaxadiol triazole derivatives induce apoptosis in HepG-2 cells through the mitochondrial pathway. Bioorg Chem. 2020 Sep;102:104078.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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