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Tubulin polymerization-IN-29

Tubulin polymerization-IN-29 (compound 6g) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-29 exhibits potent antiproliferative activity. Tubulin polymerization-IN-29 can induce HeLa cells arrest in G2/M phase[1].

Product Specifications

CAS Number

630058-59-2

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-polymerization-in-29.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C(C(C2=CC=C(F)C=C2)=O)OC3=CC=CC=C13)C4=CC(OC)=C(OC)C(OC)=C4

Molecular Formula

C25H20FNO6

Molecular Weight

449.43

References & Citations

[1]Li Q, et, al. Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors. Bioorg Chem. 2020 Sep;102:104076.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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