HDAC-IN-42
HDAC-IN-42 (compound 14f) is a potent and selective HDAC inhibitor with IC50 values of 0.19 and 4.98 μM for HDAC1 and HDAC6, respectively. HDAC-IN-42 shows anticancer and anti-proliferative activity. HDAC-IN-42 induces apoptosis and cell cycle arrest at G2/M phase[1].
Product Specifications
CAS Number
[2454024-18-9]
UNSPSC
12352005
Target
Apoptosis; HDAC
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-42.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=CC=C(OC)C=C2OC1=O)OC3=CC=CC(/C=C/C(NO)=O)=C3
Molecular Formula
C20H15NO7
Molecular Weight
381.34
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147892/HDAC-IN-42-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147892/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC6
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
PPAR alpha (PPARA) (NM_001001928) Human Over-expression Lysate
