Tubulin inhibitor 28
Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC50 value of 1.2 μM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells[1].
Product Specifications
CAS Number
[71112-91-9]
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-28.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=CC=C1SSC2=CC=CC=C2Br
Molecular Formula
C12H8Br2S2
Molecular Weight
376.13
References & Citations
[1]Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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