Tubulin inhibitor 28

Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC50 value of 1.2 μM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells[1].

Product Specifications

CAS Number

[71112-91-9]

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-28.html

Solubility

10 mM in DMSO

Smiles

BrC1=CC=CC=C1SSC2=CC=CC=C2Br

Molecular Formula

C12H8Br2S2

Molecular Weight

376.13

References & Citations

[1]Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.