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Tubulin inhibitor 28

Product Specifications

UNSPSC Description

Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC50 value of 1.2 μM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells[1].

Target Antigen

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-28.html

Solubility

10 mM in DMSO

Smiles

BrC1=CC=CC=C1SSC2=CC=CC=C2Br

Molecular Weight

376.13

References & Citations

[1]Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-147887/Tubulin-inhibitor-28-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-147887/

Clinical Information

No Development Reported

CAS Number

71112-91-9

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