HCV-IN-41

HCV-IN-41 (compound 4) is a highly potent hepatitis C virus (HCV) inhibitor with an EC50 value of 0.006762 nM, 5.183 nM, 1.365 nM and 142.2 nM for HCV genotype 1b, 2a, 3a and 4a, respectively. HCV-IN-41 reduces HCV RNA replication[1].

Product Specifications

CAS Number

2468169-71-1

UNSPSC

12352005

Target

HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hcv-in-41.html

Solubility

10 mM in DMSO

Smiles

CC(COC(N[C@H](C1=CC=CC=C1)C(N2CCC[C@H]2C(NC3=CC=C(C=C3)C4=CC=C(C=C4)NC([C@@H]5CCCN5C([C@@H](C6=CC=CC=C6)NC(OCC(C)C)=O)=O)=O)=O)=O)=O)C

Molecular Formula

C48H56N6O8

Molecular Weight

844.99

References & Citations

[1]Abdel Karim SE, et al. Symmetric benzidine derivatives as anti-HCV agents: Insight into the nature, stereochemistry of the capping amino acid and the size of the terminal capping carbamates. Bioorg Chem. 2020 Sep;102:104089.