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Antitubercular agent-28

Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 μM, an MIC value of 4.5 μM, an IC90 value of 2.5 μM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].

Product Specifications

CAS Number

2460651-10-7

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antitubercular-agent-28.html

Solubility

10 mM in DMSO

Smiles

O=C(NN1C(C2CC2)=NC3=C(C=CC=C3)C1=O)C4=CC=NC=C4

Molecular Formula

C17H14N4O2

Molecular Weight

306.32

References & Citations

[1]Patel H, et al. Synthesis and in vitro antitubercular activity of pyridine analouges against the resistant Mycobacterium tuberculosis. Bioorg Chem. 2020 Sep;102:104099.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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