Antitubercular agent-28
Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 μM, an MIC value of 4.5 μM, an IC90 value of 2.5 μM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].
Product Specifications
CAS Number
[2460651-10-7]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-28.html
Solubility
10 mM in DMSO
Smiles
O=C(NN1C(C2CC2)=NC3=C(C=CC=C3)C1=O)C4=CC=NC=C4
Molecular Formula
C17H14N4O2
Molecular Weight
306.32
References & Citations
[1]Patel H, et al. Synthesis and in vitro antitubercular activity of pyridine analouges against the resistant Mycobacterium tuberculosis. Bioorg Chem. 2020 Sep;102:104099.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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