Antitubercular agent-27
Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC50 value of 3.2 μM, an MIC value of 7.8 μM, an IC90 value of 7.0 μM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].
Product Specifications
CAS Number
2460651-09-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-27.html
Solubility
10 mM in DMSO
Smiles
O=C(NN(C(C1=C2C=CC=C1Br)=O)C2=O)C3=CC=NC=C3
Molecular Formula
C14H8BrN3O3
Molecular Weight
346.14
References & Citations
[1]Patel H, et al. Synthesis and in vitro antitubercular activity of pyridine analouges against the resistant Mycobacterium tuberculosis. Bioorg Chem. 2020 Sep;102:104099.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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