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Anti-Influenza agent 3

Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with EC50 values of 3.29, 2.45 μM for A/HK/68 (H3N2, M2-WT), A/WSN/33 (H1N1, M2-S31N) strain, respectively. Anti-Influenza agent 3 shows low cytotoxicity for MDCK epithelial cells. Anti-Influenza agent 3 inhibits the M2 WT and S31N ion channel conductivity[1].

Product Specifications

CAS Number

2481321-20-2

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anti-influenza-agent-3.html

Solubility

10 mM in DMSO

Smiles

O/N=C(C1=CC(C)=C(Cl)S1)\[C@H](C[C@@H]2C[C@H]3C2(C)C)[C@@H]3C

Molecular Formula

C16H22ClNOS

Molecular Weight

311.87

References & Citations

[1]Dong J, Xiao M, Ma Q, Zhang G, Zhao W, Kong M, Zhang Y, Qiu L, Hu W. Design and synthesis of pinane oxime derivatives as novel anti-influenza agents. Bioorg Chem. 2020 Sep;102:104106.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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