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Topoisomerase II inhibitor 12

Selected Variant

HY-147877

Size: 1 Each

Topoisomerase II inhibitor 12 (Compound 8c) is a topoisomerase II (topo II) inhibitor, working as a DNA non-intercalator. Topoisomerase II inhibitor 12 shows antineoplastic activity[1].

Product Specifications

CAS Number

2304527-20-4

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/topoisomerase-ii-inhibitor-12.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCOC1=C(C(C2=C(C3=O)C=CC=C2)=O)C3=C(C=C1)OCCCCNCCCNCCCCNCCC

Molecular Formula

C40H63N3O4

Molecular Weight

649.95

References & Citations

[1]Xie XW, et al. Design, synthesis, bioevaluation of LFC- and PA-tethered anthraquinone analogues of mitoxantrone. Bioorg Chem. 2020 Aug;101:104005.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Price

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