Aldose reductase-IN-6
Aldose reductase-IN-6 (Compound 3) is a competitive aldose reductase (AR) inhibitor with an IC50 of 3.164 μM and a Ki of 0.018 μM. Aldose reductase-IN-6 exhibits no cytotoxicity against healthy cells[1].
Product Specifications
CAS Number
2470019-41-9
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aldose-reductase-in-6.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C2=CSC(N/N=C/C3=CC=C(OCCCO4)C4=C3)=N2)C=C1
Molecular Formula
C20H16N4O2S
Molecular Weight
376.43
References & Citations
[1]Sever B, et al. Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds. Bioorg Chem. 2020 Sep;102:104110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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