ANO1-IN-3
ANO1-IN-3 (Compound 3n) is a potent and selective ANO1 inhibitor with an IC50 of 1.23 μM. ANO1-IN-3 induces apoptosis[1].
Product Specifications
CAS Number
[2494280-04-3]
UNSPSC
12352005
Target
Apoptosis; Chloride Channel
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ano1-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C3=C(OC(C)(C=C3)C)C=C2)O1)/C=C/C4=CC=CN4
Molecular Formula
C20H17NO3
Molecular Weight
319.35
References & Citations
[1]Seo Y, et al. Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors. Bioorg Chem. 2020 Aug;101:104000.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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