Apoptosis inducer 8
Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].
Product Specifications
CAS Number
2470024-51-0
UNSPSC
12352005
Target
Apoptosis; Galectin
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-8.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=CC(N2N=NC(COC3=CC=C(C4=NC5=CC(Cl)=CC=C5N4CC6=CC=CC=C6)C=C3)=C2)=C1
Molecular Formula
C29H22ClN5O2
Molecular Weight
507.97
References & Citations
[1]Sridhar Goud N, et al. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg Chem. 2020 Sep;102:104125.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Galectin-1
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