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C-Fms-IN-12

C-Fms-IN-12 (Compound 4g) is an FMS kinase inhibitor. c-Fms-IN-12 can also inhibits c-KIT. c-Fms-IN-12 is a potential broad-spectrum anticancer agent against multiple cancer types. c-Fms-IN-12 induces A549 cell apoptosis[1].

Product Specifications

CAS Number

2145102-33-4

UNSPSC

12352005

Target

Apoptosis; c-Fms; c-Kit

Type

Reference compound

Related Pathways

Apoptosis; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/c-fms-in-12-1.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CN=C(NC2=CC=C(N3CCOCC3)C=C2)N=C1OC4=CC=CC(OC)=C4)NC5=CC(OC)=CC(OC)=C5

Molecular Formula

C30H32N6O6

Molecular Weight

572.61

References & Citations

[1]Farag AK, et al. Diarylurea derivatives comprising 2,4-diarylpyrimidines: Discovery of novel potential anticancer agents via combined failed-ligands repurposing and molecular hybridization approaches. Bioorg Chem. 2020 Oct;103:104121.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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