Antileishmanial agent-12
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 14.9, 21.3 and 9.3 μM, respectively[1].
Product Specifications
CAS Number
[2482764-71-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-12.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C1=O)=C(/C=C(C)\C)C(C2=C1C=CC=C2)=O)CCC3=CN(C4=CC=CC=C4)N=N3
Molecular Formula
C25H21N3O4
Molecular Weight
427.45
References & Citations
[1]Pertino MW, et al. Synthesis, trypanocidal and anti-leishmania activity of new triazole-lapachol and nor-lapachol hybrids. Bioorg Chem. 2020 Oct;103:104122.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
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