Tubulin polymerization-IN-27
Tubulin polymerization-IN-27 (compound 5j) is a tubulin polymerization inhibitor. Tubulin polymerization-IN-27 can arrest cell cycle at G2/M phase and induce apoptosis[1].
Product Specifications
CAS Number
2462030-32-4
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-27.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C=CC=CC2=C(C3=NNC=C3C4=CC=C(OCC)C=C4)C=C1
Molecular Formula
C22H20N2O2
Molecular Weight
344.41
References & Citations
[1]Wang G, et, al. Design, synthesis, molecular modeling, and biological evaluation of pyrazole-naphthalene derivatives as potential anticancer agents on MCF-7 breast cancer cells by inhibiting tubulin polymerization. Bioorg Chem. 2020 Oct;103:104141.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
43925124 3x 1.0µg DNA
SLC1A4 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Sign In for Pricing
View Details 
OR1002500-01 100 mg
(4R,4'R) -2,2'- (Cyclopropane-1,1-diyl) bis (4-isopropyl-4,5-dihydrooxazole)
Sign In for Pricing
View Details OR1002500-02 250 mg
(4R,4'R) -2,2'- (Cyclopropane-1,1-diyl) bis (4-isopropyl-4,5-dihydrooxazole)
Sign In for Pricing
View Details OR1002500-03 1 g
(4R,4'R) -2,2'- (Cyclopropane-1,1-diyl) bis (4-isopropyl-4,5-dihydrooxazole)
Sign In for Pricing
View Details