Topoisomerase II inhibitor 10
Selected Variant
HY-147839
Size: 1 Each
Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC50 value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells[1].
Product Specifications
CAS Number
2488208-96-2
UNSPSC
12352005
Target
Apoptosis; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-ii-inhibitor-10.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(NC(CSC2=NN=C3N2N(CC(NC4=CC=C(C(O)=O)C=C4)=O)C(C5=C3C=CC=C5)=O)=O)C=C1
Molecular Formula
C27H20N6O7S
Molecular Weight
572.55
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
Price
Frequently Asked Questions
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