KFU-127
KFU-127 (Compound 6b) is a broad spectrum topical antimicrobial capable of one-shot targeting of bacterial and fungal-bacterial biofilms. KFU-127 is considerably toxic for eukaryotic cells[1]. KFU-127 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
UNSPSC
12352005
Target
Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kfu-127.html
Solubility
10 mM in DMSO
Smiles
CCCC1OCC2=C(C(C[N+](C/C=C/C#CC(C)(C)C)(CC3=C4C=CC=CC4=CC=C3)C)=NC(C)=C2O1)CO.[Br-]
Molecular Formula
C34H43BrN2O3
Molecular Weight
607.62
References & Citations
[1]Garipov MR, et al. Targeting pathogenic fungi, bacteria and fungal-bacterial biofilms by newly synthesized quaternary ammonium derivative of pyridoxine and terbinafine with dual action profile. Bioorg Chem. 2020 Nov;104:104306.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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