HIF-1α-IN-3
HIF-1α-IN-3 (Compound (S) -3f) is a hypoxia-selective HIF-1α inhibitor. HIF-1α-IN-3 shows strong antiestrogenic potency[1].
Product Specifications
CAS Number
2170715-64-5
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hif-1α-in-3.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(C2=CC=CC=C2)[N+]([O-])=C3C=CC(N4C[C@@H](N)CC4)=CC3=[N+]1[O-]
Molecular Formula
C19H17N5O2
Molecular Weight
347.37
References & Citations
[1]Buravchenko GI, et al. Discovery of derivatives of 6 (7) -amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency. Bioorg Chem. 2020 Nov;104:104324.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10324235 96 Well
Porcine Coiled coil domain containing protein 75 (CCDC75) ELISA Kit
Sign In for Pricing
View Details 
H00026269-P02-10ug 10 µg
Recombinant Human FBXO8 Protein - (Dry Ice)
Sign In for Pricing
View Details 
25685066 1.0 µg DNA
KIF3B Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details