FGFR4-IN-12
FGFR4-IN-12 (Compound A34) is a potent inhibitor of FGFR4. FGFR4-IN-12 exhibits improved FGFR4 inhibitory capability and selectivity and excellent anti-proliferative activities against FGFR4-dependent HCC cell lines. FGFR4-IN-12 has the potential for the research of cancer diseases[1]. FGFR4-IN-12 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
2423992-63-4
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr4-in-12.html
Solubility
10 mM in DMSO
Smiles
CC#CC(NC1=C(N2[C@H]3C[C@H](OC3)C2)C=C(C(C4=NC=C(C=C(C5=C(C(OC)=CC(OC)=C5Cl)Cl)C(N6CC)=O)C6=C4)=C1)OC)=O
Molecular Formula
C34H32Cl2N4O6
Molecular Weight
663.55
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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