FPDT
Product Specifications
UNSPSC Description
FPDT is an anti-glioblastoma agent. FPDT displays the IC50 value of 45–68 μM for GBM cells and >100 μM for astrocytes. Anti-glioblastoma activity of FPDT is linked to downregulation of the AKT pathway[1].
Target Antigen
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fpdt.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C(O)=C1)C2=CC=C(S2)NC3=CC=C(C=C3)F
Molecular Weight
301.34
References & Citations
[1]Szeliga M, et al. Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway. Bioorg Chem. 2020;105:104362.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147789/FPDT-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147789/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal PDE4B Antibody (OTI1D12) [DyLight 488]](https://cdn.genprice.uk/genprice/genprice5.png)
![Aminoacylase 1 (ACY1) Mouse Monoclonal Antibody [Clone ID: AT1E2]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd905/imageurl/am50353pu-s.webp)
AM50353PU-S 50 µL
Aminoacylase 1 (ACY1) Mouse Monoclonal Antibody [Clone ID: AT1E2]
Ask
View Details