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Urease-IN-3

Urease-IN-3 (Compound L12) is a potent inhibitor of Urease with an IC50 of 1.449 μM. Urease-IN-3 is a flavonoid analogue compound[1].

Product Specifications

CAS Number

[2543651-72-3]

UNSPSC

12352005

Target

Bacterial; Urease

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/urease-in-3.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N/N=C/C1=C(O)C=CC2=C1OC(C3=CC=C(F)C=C3)=CC2=O)C4=CC=CC=C4

Molecular Formula

C23H15FN2O4

Molecular Weight

402.37

References & Citations

[1]Liu H, et al. Flavonoid analogues as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation. Bioorg Chem. 2020;105:104370.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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