Pim-1 kinase inhibitor 2
Pim-1 kinase inhibitor 2 (Compound 13) is a potent inhibitor of Pim-1 kinase. Pim-1 kinase inhibitor 2 induces apoptosis. Pim-1 kinase inhibitor 2 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
[2543624-91-3]
UNSPSC
12352005
Target
Apoptosis; Pim
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-1-kinase-inhibitor-2.html
Purity
99.91
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=C(N=C(C=C1C2=CC=CO2)C3=CC=C(C=C3)N4C(C5=CC=CC=C5C4=O)=O)N
Molecular Formula
C24H14N4O3
Molecular Weight
406.39
References & Citations
[1]Farrag AM, et al. New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study. Bioorg Chem. 2020;105:104378.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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