Anti-inflammatory agent 23
Anti-inflammatory agent 23 (Compound 4m) is an anti-inflammatory agent. Anti-inflammatory agent 23 inhibits the production of NO activated by LPS with an IC50 of 0.449 μM. Anti-inflammatory agent 23 has a good affinity for p65 protein[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-23.html
Solubility
10 mM in DMSO
Smiles
CC(O[C@H]1CC[C@]2(C(C1)=CCC3C4CC5O[C@@H]([C@H](C5[C@]4(CCC32)C)C)CC[C@H](CN6C=C(C(OC6=O)=O)C)C)C)=O
Molecular Formula
C34H49NO6
Molecular Weight
567.76
References & Citations
[1]Michalak O, et al. Synthesis and anti-tumour, immunomodulating activity of diosgenin and tigogenin conjugates. J Steroid Biochem Mol Biol. 2020 Apr;198:105573.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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