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Anti-inflammatory agent 23

Anti-inflammatory agent 23 (Compound 4m) is an anti-inflammatory agent. Anti-inflammatory agent 23 inhibits the production of NO activated by LPS with an IC50 of 0.449 μM. Anti-inflammatory agent 23 has a good affinity for p65 protein[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-23.html

Solubility

10 mM in DMSO

Smiles

CC(O[C@H]1CC[C@]2(C(C1)=CCC3C4CC5O[C@@H]([C@H](C5[C@]4(CCC32)C)C)CC[C@H](CN6C=C(C(OC6=O)=O)C)C)C)=O

Molecular Formula

C34H49NO6

Molecular Weight

567.76

References & Citations

[1]Michalak O, et al. Synthesis and anti-tumour, immunomodulating activity of diosgenin and tigogenin conjugates. J Steroid Biochem Mol Biol. 2020 Apr;198:105573.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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