HCV-IN-40
HCV-IN-40 (Compound 18c) is a potent, orally active hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.259, 0.434 and 0.069 μM against GT1a, GT1b and GT1b CES1 replicons[1].
Product Specifications
CAS Number
2087916-66-1
UNSPSC
12352005
Target
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hcv-in-40.html
Solubility
10 mM in DMSO
Smiles
CCOC(C(C)(N[P@](OC[C@H]1O[C@H]([C@@](Br)([C@@H]1O)F)N2C=CC(NC2=O)=O)(OC3=CC=CC=C3)=O)C)=O
Molecular Formula
C21H26BrFN3O9P
Molecular Weight
594.32
References & Citations
[1]Chris Krueger A, et al. Synthesis and evaluation of 2'-dihalo ribonucleotide prodrugs with activity against hepatitis C virus. Bioorg Med Chem. 2020 Jan 1;28 (1) :115208.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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